Pharmacogenomic (PGx) testing · MHRA registered · UKCA marked

Is your medicine right for you?

One saliva sample, 47 individual genetic tests. Find out which medicines are likely to work for you, and which may cause side effects. Ordered online, done at home, and useful for the rest of your life.

Research-backed

Free UK delivery

Results in 4–6 weeks

NICE-aligned

Data never shared

Helps with medicines for

12 genes · 78 medicines

One test, results for life

Recommended by NICE for Clopidogrel

AS FEATURED IN · AWARD-WINNING · MHRA REGISTERED

THE EVIDENCE

Built on PREPARE, the largest trial of its kind

Every Mantara report follows the protocol tested in the PREPARE trial: nearly 7,000 patients in 7 European countries, published in The Lancet in 2023.

~7,000

patients in 7 European countries took part in the trial

30%

fewer serious side effects with genotype-guided prescribing in the trial

MHRA

registered, and CE and UKCA marked in the UK

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01 · WHY WOULD I NEED A TEST?

Medicines don’t work the same for everyone

Up to 90% of common medicines only work well for 30–50% of the people who take them. Often, the reason is written in your genes.

Statins giving you muscle aches?

Around 1 in 3 people process some statins slowly, so the drug builds up and causes pain or fatigue. A different statin, or a different dose, may suit you better.

Cholesterol · Statins

Antidepressants not helping, or too many side effects?

Your genes affect how quickly your body clears many antidepressants. Too fast and they don’t work; too slow and side effects build up.

Anxiety · Depression

Had a stroke and taking Clopidogrel?

About 30% of people carry a variant that makes Clopidogrel less effective. NICE now recommends a genetic test before it is prescribed.

Stroke · Heart

02 · IS MY MEDICINE COVERED?

Check your medicine in seconds

Type the name of a medicine you take. We’ll show whether the Mantara PGx Panel Test gives your clinician guidance on it, and which gene is involved.

Four steps, all from home

No needles, no clinic visit. Just 1 ml of saliva, collected at home. (Clinicians can also send an EDTA blood sample or take saliva in clinic.)

Order online

Kits arrive in 2–3 working days. Order before midday and we dispatch the same day.

Collect your sample

Collect a small saliva sample, register your kit online, and post it back in the prepaid envelope.

We analyse 12 genes

Our specialist partner laboratory in Germany analyses 12 of your genes, including 47 alleles, to understand how your body may respond to 78 different medicines.

Your report, for life

A clear, personalised report is emailed securely within 4–6 weeks, ready to share with your GP or consultant.

04 · WHAT WILL MY REPORT TELL ME?

Actionable recommendations, not raw data.

Every medicine gets a plain-English verdict and a dose note your clinician can act on. No gene jargon unless you want it.

Medicine-by-medicine verdicts

Traffic-light guidance across 78 medicines, grouped by condition.

Swipe to see the full table →

Atorvastatin

Cholesterol

SLCO1B1

Use as normal

Simvastatin

Cholesterol

SLCO1B1

Increased side-effect risk · consider alternative

Clopidogrel

Stroke prevention

CYP2C19

Poor metaboliser · alternative recommended

Sertraline

Depression · anxiety

CYP2C19

Consider lower starting dose

Omeprazole

Acid reflux

CYP2C19

Use as normal

genes from the UPGx panel published in The Lancet

CYP2B6

CYP2C9

CYP2C19

CYP2D6

CYP3A5

DPYD

HLA-B

SLCO1B1

TPMT

UGT1A1

VKORC1

78 medicines, 5 areas

Mental health · Heart & circulation · Pain · Digestive · Long-term conditions. Only medicines with actionable PGx evidence.

Written for two readers

A plain-English summary for you, and a referenced clinical section for your GP or consultant.

Yours for life

Genes don’t change. Your report stays valid for every future prescription, and we update guidance as evidence evolves.

05 · WHICH TEST DO I NEED?

Two tests. One clear route to each.

Most people choose the full panel. The rapid Clopidogrel test is taken by a healthcare professional, so we guide you to one of our partner clinicians.

Mantara® PGx Panel Test

£429

one-off · or 3 × £143 with Klarna

The complete picture: 12 genes, 78 commonly prescribed medicines across mental health, heart, pain and digestive care.

At-home saliva sample, free UK delivery

Results in 4–6 weeks, useful for life

Clear report to share with your GP or consultant

MHRA registered · CE & UKCA marked

NEW · VIA A HEALTHCARE PROFESSIONAL

Rapid Clopidogrel (CYP2C19) Test

Results in days

cheek swab, taken by a clinician

A fast, focused test for people prescribed Clopidogrel after a stroke or heart attack, in line with NICE 2024 guidance. The swab must be taken by a healthcare professional, so choose your route:

I’m a patient → we connect you with a partner clinician near you

I’m a clinician, pharmacist or nurse → order directly for your patients

Also included in the PGx Panel Test

YOUR DATA

Your genetic data stays private

Stored separately

Your personal details and your genetic data are kept in separate systems, linked only by a randomly generated code.

Encrypted

Encrypted in transit and at rest, to strict UK GDPR standards.

No DNA sequencing

We only check the gene variants that affect medicines.

Never shared

Your genetic data is never shared or sold. You decide who sees your report.

Why the right medicine matters

Figures from NHS England, NICE and peer-reviewed studies.

1 in 20

hospital beds in the UK are occupied because of an adverse drug reaction

£2.2bn

the estimated annual cost of adverse drug reactions to the NHS

~30%

fewer clinically significant adverse reactions when prescribing is guided by PGx

30–50%

of patients respond well to the most common medicines. The rest are guessing

06 · WHY CHOOSE MANTARA?

Founded by doctors. Built for real prescribing decisions.

Mantara Health was founded by UK doctors who believe every patient deserves truly personalised care. Our panel is deliberately focused: only genes and medicines with the strongest, clinically actionable evidence make the cut.

12 key genes

A far more complete picture than tests that look at one or two genes.

78 medicines covered

Only medications backed by the strongest, clinically actionable PGx evidence.

Your data stays yours

Encrypted, UK GDPR-compliant, and never shared with industry partners.

CE & UKCA marked

Approved by the MHRA and manufactured to rigorous quality standards.

Film to be recorded 14/10 · 2 min

MEET OUR FOUNDER

Why a group of doctors started Mantara

Dr Mark Hudson-Peacock, Chairman and Medical Director, explains in two minutes how a PGx test works, who it helps most and how your GP uses the report.

Mantara was founded in 2020 by doctors who saw how often standard medicines cause side effects, repeat prescriptions and avoidable hospital admissions.

REAL PATIENTS · CONSENTED REVIEWS

“The change I made improved my quality of life significantly.”

←

→

Statins · Cholesterol

“I was taking statins but started experiencing muscle pain and fatigue. The test showed I’m a poor metaboliser of the statin I’d been prescribed. My doctor switched me to one that suits my genetic profile, and I manage my cholesterol without the horrible side effects.”

Ms S, Cotswolds

Verified Mantara customer

Pain relief · Post-surgery

“After surgery the usual painkillers weren’t helping much. The test found I’m a poor metaboliser of certain opioids, no wonder they weren’t working. My doctor switched me to something more suitable and the difference was huge.”

Mr B, Oxford

Verified Mantara customer

Antidepressants · Mental health

“I’d struggled with side effects from several antidepressants. The test identified that I metabolise some drugs too quickly and others too slowly. With that insight my doctor changed my medication and I finally feel more stable.”

Mr M, Somerset

Verified Mantara customer

Rated Excellent · Google Reviews

FOR GPs, CONSULTANTS, PHARMACISTS & CLINICS

Prescribe with confidence. Partner with Mantara.

Clinically actionable recommendations from the Dutch Pharmacogenetics Working Group (DPWG), the same protocol used in the UPGx study published in The Lancet, plus a rapid CYP2C19 pathway for patients on Clopidogrel.

Peer-reviewed evidence pack and CPD-style clinician guide

Bulk ordering, monthly reconciliation and a partner portal (coming)

Practice pricing for kits you stock, with lab fees invoiced only when a sample is registered

Members of the MHRA, BIVDA and CERSI-PGx group. Send an EDTA blood sample or take saliva in clinic

RESOURCE CENTRE

Plain-English guides to your medicines and your genes

MENTAL HEALTH

Sertraline not working, or side effects too strong? Your genetics may explain it

HEART & STROKE

Taking Clopidogrel? Here’s why a PGx test could make a difference

CHOLESTEROL

Simvastatin and muscle pain: the gene that changes your risk

07 · STILL GOT QUESTIONS?

Everything people ask before they order

Still unsure? Book a free 10-minute call with one of our team. No pressure, no jargon.

Is the test right for me?

It helps most if you take medicine for a long-term condition, have had side effects before, or want to know which medicines are likely to work for you. It does not cover every medicine, so your clinician can help you decide.